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  <xs:element id="ttwo_A2029NotesMember" abstract="true" name="A2029NotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
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  <xs:element id="ttwo_A2026ConvertibleNotesMember" abstract="true" name="A2026ConvertibleNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_A2024ConvertibleNotesMember" abstract="true" name="A2024ConvertibleNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_ShortTermDebtGross" abstract="false" name="ShortTermDebtGross" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_ShortTermDebtUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" abstract="false" name="ShortTermDebtUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_A2024NotesMember" abstract="true" name="A2024NotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_TermLoanMember" abstract="true" name="TermLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_DebtMaturityRemainderOfFiscalYear" abstract="false" name="DebtMaturityRemainderOfFiscalYear" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DebtMaturityYearOne" abstract="false" name="DebtMaturityYearOne" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DebtMaturityYearTwo" abstract="false" name="DebtMaturityYearTwo" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DebtMaturityYearThree" abstract="false" name="DebtMaturityYearThree" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DebtMaturityYearFour" abstract="false" name="DebtMaturityYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DebtMaturityAfterYearFour" abstract="false" name="DebtMaturityAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DebtGrossBeforeFairValueAdjustments" abstract="false" name="DebtGrossBeforeFairValueAdjustments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DebtFairValueAdjustments" abstract="false" name="DebtFairValueAdjustments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_ZyngaIncMember" abstract="true" name="ZyngaIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_A2029And2034NotesMember" abstract="true" name="A2029And2034NotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_A20252027And2032NotesMember" abstract="true" name="A20252027And2032NotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_DebtInstrumentChangeOfControlPurchasePricePercent" abstract="false" name="DebtInstrumentChangeOfControlPurchasePricePercent" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="ttwo_DebtInstrumentEventOfDefaultPercentOfPrincipalThreshold" abstract="false" name="DebtInstrumentEventOfDefaultPercentOfPrincipalThreshold" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="ttwo_A2022CreditAgreementMember" abstract="true" name="A2022CreditAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_LineOfCreditFacilityOptionalIncreaseAdditionalBorrowings" abstract="false" name="LineOfCreditFacilityOptionalIncreaseAdditionalBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_LineOfCreditFacilityOptionalIncreaseAdditionalBorrowingsPercent" abstract="false" name="LineOfCreditFacilityOptionalIncreaseAdditionalBorrowingsPercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="ttwo_A025ConvertibleSeniorNotesDue2024Member" abstract="true" name="A025ConvertibleSeniorNotesDue2024Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_A0ConvertibleSeniorNotesDue2026Member" abstract="true" name="A0ConvertibleSeniorNotesDue2026Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuableEntitySharesIssuedPerAcquireeShare" abstract="false" name="BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuableEntitySharesIssuedPerAcquireeShare" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="ttwo_BusinessAcquisitionCashPrice" abstract="false" name="BusinessAcquisitionCashPrice" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:perShareItemType"/>
  <xs:element id="ttwo_DebtInstrumentConvertiblePrincipalTenderedForCash" abstract="false" name="DebtInstrumentConvertiblePrincipalTenderedForCash" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DebtInstrumentConvertiblePrincipalConvertedIntoReferenceProperty" abstract="false" name="DebtInstrumentConvertiblePrincipalConvertedIntoReferenceProperty" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_PaymentsForTenderedAndConvertedDebt" abstract="false" name="PaymentsForTenderedAndConvertedDebt" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_ZyngaV.s.IBMMember" abstract="true" name="ZyngaV.s.IBMMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_EffectiveIncomeTaxRateReconciliationDivestituresAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationDivestituresAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_EffectiveIncomeTaxRateReconciliationGeographicMixOfEarningsAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationGeographicMixOfEarningsAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_GearboxMember" abstract="true" name="GearboxMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_BusinessCombinationConsiderationTransferredDeferredPayment" abstract="false" name="BusinessCombinationConsiderationTransferredDeferredPayment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_BusinessCombinationConsiderationTransferredSettlement" abstract="false" name="BusinessCombinationConsiderationTransferredSettlement" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DevelopedGameTechnologyMember" abstract="true" name="DevelopedGameTechnologyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_GameEngineTechnologyMember" abstract="true" name="GameEngineTechnologyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_GamesInDevelopmentMember" abstract="true" name="GamesInDevelopmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherAssets" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_AdvertisingTechnologyMember" abstract="true" name="AdvertisingTechnologyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_FiniteLivedIntangibleAssetsDivested" abstract="false" name="FiniteLivedIntangibleAssetsDivested" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ttwo_DeveloperRelationshipsMember" abstract="true" name="DeveloperRelationshipsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_DepreciationAndAmortizationMember" abstract="true" name="DepreciationAndAmortizationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_A2024PlanMember" abstract="true" name="A2024PlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="ttwo_EmployeeSeveranceAndEmployeeRelatedCostsMember" abstract="true" name="EmployeeSeveranceAndEmployeeRelatedCostsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_EmployeeRelatedCostsMember" abstract="true" name="EmployeeRelatedCostsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_TitleCancellationsMember" abstract="true" name="TitleCancellationsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_LossOnDivestituresMember" abstract="true" name="LossOnDivestituresMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_OfficeSpaceReductionsMember" abstract="true" name="OfficeSpaceReductionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_ImpairmentLossOfRightOfUseAssetMember" abstract="true" name="ImpairmentLossOfRightOfUseAssetMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_ProfessionalFeesMember" abstract="true" name="ProfessionalFeesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_StraussZelnickMember" abstract="true" name="StraussZelnickMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_KarlSlatoffMember" abstract="true" name="KarlSlatoffMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ttwo_MichaelShereskyMember" abstract="true" name="MichaelShereskyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
